Structure of PDB 8k60 Chain J Binding Site BS02

Receptor Information
>8k60 Chain J (length=249) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GALRFGVLGPVRAWRDGETLATGSPQQRALLAALLLREGRTATAGELIDA
LWGEEPPSQALAAVRTYASRLRKVLDPGVLVSESGGYAVRGLAEGALDLA
RAQDLASAAEKARSAGDLCHARDLLRRALDLWDGEVLAGVPGPYAQTQRV
RLGEWRLQLLETRLDMDLDQGCHAEAVSELTALTAAHPLRERLRELLMLA
LYRSGRQAEALAVYADTRRLLADELGVDPRPGLQELQQRILQADPALAE
Ligand information
>8k60 Chain H (length=57) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tgcatccgtgagtcgagggtaataaccagggggagataaacgaacgctga
acgctcc
Receptor-Ligand Complex Structure
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PDB8k60 Structural insights into transcription activation of the Streptomyces antibiotic regulatory protein, AfsR
Resolution3.4 Å
Binding residue
(original residue number in PDB)		R87 S91 K95 G107
Binding residue
(residue number reindexed from 1)		R65 S69 K73 G85
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0031409 pigment binding
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8k60, PDBe:8k60, PDBj:8k60
PDBsum8k60
PubMed39108719
UniProtP25941|AFSR_STRCO Regulatory protein AfsR (Gene Name=afsR)

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