Structure of PDB 8a63 Chain J Binding Site BS02

Receptor Information

>8a63 Chain J (length=175) Species: 169963 (Listeria monocytogenes EGD-e) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NRLKDQYLKEIVPALMSKFNYDSVMEVPKIDKIVINTGVGDATANAKVLD
SAVEELALITGQKPVITKAKNSIAGFRLREGMPIGAKVTLRGERMYDFLD
KLVTVSLPRVRDFRGVSKKAFDGRGNYTLGVREQLIFPEIDYDQVSKVRG
MDVVIVTTAKSDEESHELLTQLGMP

Ligand information

>8a63 Chain B (length=114) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cugguaguuauggcgagaaggucacacccguucccauaccgaacacggua
guuaagcuucucugcgccaaugguaguugggggcuucccccugcgagagu
aggucgcugccggg

<<<<<<<<....<<<<<<<<.....<<<<<...............>>>..
>>....>>>>>>.>><<<.......<<.<<<<<...>>>>>.>>......
.>>>.>>>>>>>>.

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8a63 Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes.
Resolution	3.1 Å
Binding residue (original residue number in PDB)	S24 M26 E27 Q63 K64 V66 I67 K69 T90 R92
Binding residue (residue number reindexed from 1)	S23 M25 E26 Q62 K63 V65 I66 K68 T89 R91

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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External links

PDB	RCSB:8a63, PDBe:8a63, PDBj:8a63
PDBsum	8a63
PubMed	36300626
UniProt	Q927L9\|RL5_LISMO Large ribosomal subunit protein uL5 (Gene Name=rplE)

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