Structure of PDB 7p7q Chain J Binding Site BS02

Receptor Information

>7p7q Chain J (length=177) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NRLKEKYIKEVTPSLVEKFNYSSVMQTPKVDKIVINMGVGDAVSNAKNLD
KAVEELALITGQKPLITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLD
KLVTVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRG
MDIVIVTTANTDEESRELLAQLGMPFQ

Ligand information

>7p7q Chain B (length=114) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gugguggcgauagcgagaaggauacaccuguucccaugccgaacacagaa
guuaagcuucuuagcgccgauuguagugaaggguuucccuuugugagagu
aggacgucgccacg

<<<<<<<<....<<<<<<<<.....<<<<<...............>>>..
>>....>>>>>>.>>.<<.......<<<<<<<<...>>>>>>>>......
.>>..>>>>>>>>.

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7p7q Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Resolution	2.4 Å
Binding residue (original residue number in PDB)	S24 M26 Q27 Q63 K64 L66 K69 T90 R92
Binding residue (residue number reindexed from 1)	S23 M25 Q26 Q62 K63 L65 K68 T89 R91

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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External links

PDB	RCSB:7p7q, PDBe:7p7q, PDBj:7p7q
PDBsum	7p7q
PubMed	35387982
UniProt	Q839F2\|RL5_ENTFA Large ribosomal subunit protein uL5 (Gene Name=rplE)

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