Structure of PDB 7obr Chain J Binding Site BS02

Receptor Information

>7obr Chain J (length=169) Species: 9986 (Oryctolagus cuniculus)

ENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVR
SFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFG
IQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRIS
KEEAMRWFQQKYDGIILPG

Ligand information

>7obr Chain 7 (length=120)

gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga
auaccgggugcuguaggcuu

<<<<<<<<<....<<<<<<<<.....<<<<<..............>>>..
>>....>>>>>>.>><<<<<<<.....<<.<<..<<....>>.>>.>>..
..>>>>>>>>>>>>>>>>..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7obr Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle.
• Resolution: 2.8 Å
• Binding residue (original residue number in PDB): M12 R13 Q46 T47 V49 C72 T73 R75 P137 G138 S140 I141 D143 K145 C150 G152 A153 H155
• Binding residue (residue number reindexed from 1): M4 R5 Q38 T39 V41 C64 T65 R67 P129 G130 S132 I133 D135 K137 C142 G144 A145 H147

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7obr, PDBe:7obr, PDBj:7obr
• PDBsum: 7obr
• PubMed: 34260909
• UniProt: G1TUB8|RL11_RABIT Large ribosomal subunit protein uL5 (Gene Name=RPL11)