Structure of PDB 7at8 Chain J Binding Site BS02

Receptor Information
>7at8 Chain J (length=105) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEIL
ELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQS
VLLPK
Ligand information
>7at8 Chain U (length=156) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atacaggatgtatatatatctgacacgtgcctggagactagggagtaatc
cccttggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggt
gctagagctgtctacgaccaattgagcggcctcggcaccgggattctcca
gtatga
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7at8 Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		R20 G28 R32 R77
Binding residue
(residue number reindexed from 1)		R7 G15 R19 R64
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7at8, PDBe:7at8, PDBj:7at8
PDBsum7at8
PubMed33211010
UniProtP06897|H2A1_XENLA Histone H2A type 1

[Back to BioLiP]