BioLiP

Receptor Information

>6s8b Chain J (length=475) Species: 930945 (Sulfolobus islandicus REY15A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

EELLMSLKLKALYPLTGGYNRHSINPFYEELVRPTEIKGLWRWWNRVLFN
TLAYSTKGKLYTYESIDRLFEDVFGSENKKSAVRLEVITDEGNDNRFELS
YVELDKVIDCLRNYKRKVSLDFIDNTLIAEIEGSTKIPISFKSNLDIDKI
IKDLVHNNKLLSFELLGFKSVEIDATKISDKKILKEILRDLITNYLEYFN
IKQEVTFTLNIYLDKSREHKQNFEDKLKFALYSLLVFILLGGIGRKTSRG
FGSLSIIDVKCYDNSICKKIEDLAKNFLKISSGNELKSKIESILDCIKNS
CIDTLYIENNILSEIDPKKNVVYFINSDLFEVKRINDKEKVLANIYKAVS
SEGCCIKSIITDKYVRKSFLIAFGGYRKVEKDKGLDIGFIKNYLCETCET
VSSFNIVDFLLSEGSFMSDYILQYEHRNSLLRFKLISDNSNNSYLIGYIL
HSSYFKKIDIKYVRCILEKLTYCVI

>6s8b Chain V (length=49) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

auugaaaguucaaagcuuagauacccuggagggaaaccagacuuaacac

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Receptor-Ligand Complex Structure

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Structure summary

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PDB	6s8b Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Resolution	2.41 Å
Binding residue (original residue number in PDB)	G18 R22 R34 T36 E37 K39 G40 L41 R43 G76 S77 E78 K80 K81 S82 F164 R246 K247 S249 R250 Y347 V350 S351 S352 K368 G375 Y377 R378 H427 R428 N429
Binding residue (residue number reindexed from 1)	G17 R21 R33 T35 E36 K38 G39 L40 R42 G75 S76 E77 K79 K80 S81 F163 R245 K246 S248 R249 Y346 V349 S350 S351 K367 G374 Y376 R377 H426 R427 N428

Enzyme Commision number

	Biological Process
GO:0051607	defense response to virus

PDB	RCSB:6s8b, PDBe:6s8b, PDBj:6s8b
PDBsum	6s8b
PubMed	32730741
UniProt	F0NDX4

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Structure of PDB 6s8b Chain J Binding Site BS02