Structure of PDB 6hb4 Chain J Binding Site BS02
Receptor Information
>6hb4 Chain J (length=193) Species:
9606
(Homo sapiens) [
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SVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPD
SKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAM
TKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLS
DSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRTIK
Ligand information
>6hb4 Chain K (length=22) [
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ctgtgcagacattcaattgtta
Receptor-Ligand Complex Structure
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PDB
6hb4
DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region.
Resolution
3.05 Å
Binding residue
(original residue number in PDB)
K51 K52 V54 L58 K62 K69 K139 M143 R157 Y162 Q179 L182 K183 K186 W189 Y211 R232
Binding residue
(residue number reindexed from 1)
K8 K9 V11 L15 K19 K26 K96 M100 R114 Y119 Q136 L139 K140 K143 W146 Y168 R189
Binding affinity
PDBbind-CN
: Kd=4.4nM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6hb4
,
PDBe:6hb4
,
PDBj:6hb4
PDBsum
6hb4
PubMed
31114891
UniProt
Q00059
|TFAM_HUMAN Transcription factor A, mitochondrial (Gene Name=TFAM)
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