Structure of PDB 5zwm Chain J Binding Site BS02

Receptor Information
>5zwm Chain J (length=304) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LQKQQEEEELKRKLKQEEDEKDKRKLIESGPNLELHEDKFLLDLSKFKIY
YDNNHGYEWWDTAYLVAHPLPEKIIKAYLTQHERKRLRRNRRKMAREARE
IKIKLGLLPKPEPKVKLSNMMSVFENDQNITDPTAWEKVVKDQVDLRKRK
HLEENERRHEDAIKRRKEAVNMNVEKPTVYHCKVFQFKNLQNPKIRFKLK
MNSKELSLKGLCLRIRDDGPGIIIVVGNEKSCKFYENLVMKRIKWNEDFE
LHIKMDMHNNSISKTWEGYLQDCKFKGWFMKVCNDQDSLLRTLGQFDSEH
FYSP
Ligand information
>5zwm Chain I (length=110) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auccuuaugcacgggaaauacgcauaucagugaggauucguccgagauug
uguuuuugcugguuuaauuauaacuccucauggucagacuauguagggaa
uuuuuggaau
...................<<<<<.<<<.....<<<....>>>..>>>>>
>>>.....................<<<<<<<<<<<.>>>>>>>.>>>>..
..........
Receptor-Ligand Complex Structure
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PDB5zwm Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Resolution3.4 Å
Binding residue
(original residue number in PDB)		R241 R245 R246 R249 K273 K305 H308
Binding residue
(residue number reindexed from 1)		R84 R88 R89 R92 K116 K148 H151
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000387 spliceosomal snRNP assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005687 U4 snRNP
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zwm, PDBe:5zwm, PDBj:5zwm
PDBsum5zwm
PubMed29794219
UniProtQ03338|PRP3_YEAST U4/U6 small nuclear ribonucleoprotein PRP3 (Gene Name=PRP3)

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