Structure of PDB 5ylz Chain J Binding Site BS02

Receptor Information
>5ylz Chain J (length=432) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KGGVWTNVEDQILKAAVQKYGTHQWSKVASLLQKKTARQSELRWNEYLNP
KLNFTEFSKEEDAQLLDLARELPNQWRTIADMMARPAQVCVERYNRLLES
EDSEDEEKEMLAEARARLLNTQGKKATRKIRERMLEESKRIAELQKRREL
KQAGINVAIKKPKKKYGTDIDYNEDIVYEQAPMPGIYDTSTEDRQIKKKF
EQFERKVNRKGLLTPKELLPHDSGQEDNERSNIKSGKQLKSRIRKFFASL
PSPKNDFEIEDEKEEDAEIAEYEKEEDNFIEPPSQPRVSLVAVPLAYSTL
KNNPQSAIDNKYNLLVANAINKEPHMESRMQHITQGRTSMKIQFKTAMPP
TEVLLESIQSKVESIEQLQRKLQHVQPLEQQNNEMCSTLCHHSLPALIEG
QRKYYADYYAYRQEIRSLEGRRKRLQAMLNSS
Ligand information
>5ylz Chain E (length=62) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auaaauuuuuaagguauguauuuauuuuuuuuaagaacuagauacuaaca
caaauaguaaau
..................................................
............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5ylz Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae
Resolution3.6 Å
Binding residue
(original residue number in PDB)		E147 K204
Binding residue
(residue number reindexed from 1)		E106 K163
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000386 second spliceosomal transesterification activity
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0000350 generation of catalytic spliceosome for second transesterification step
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
GO:0071006 U2-type catalytic step 1 spliceosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5ylz, PDBe:5ylz, PDBj:5ylz
PDBsum5ylz
PubMed29153833
UniProtQ03654|CEF1_YEAST Pre-mRNA-splicing factor CEF1 (Gene Name=CEF1)

[Back to BioLiP]