Structure of PDB 5t16 Chain J Binding Site BS02

Receptor Information
>5t16 Chain J (length=267) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPTKAGDIVKATKWPPKLPEIQDLAIRARVFIHKSTIKDKVYLSGSEMIN
AHNERLEFLGDSILNSVMTLIIYNKFPDYSEGQLSTLRMNLVSNEQIKQW
SIMYNFHEKLKTNFDLKDENSNFQNGKLKLYADVFEAYIGGLMEDDPRNN
LPKIRKWLRKLAKPVIEEATRNQVKLDMNAKRQLYSLIGYASLRLHYVTV
KKPTAVDPNSIVECRVGDGTVLGTGVGRNIKIAGIRAAENALRDKKMLDF
YAKQRAAIPRSESVLKD
Ligand information
>5t16 Chain P (length=34) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gccaugucaugucaugaguccauggcauggcaug
..<<<<<<<<<<<<<<....>>>>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB5t16 The Functional Cycle of Rnt1p: Five Consecutive Steps of Double-Stranded RNA Processing by a Eukaryotic RNase III.
Resolution2.783 Å
Binding residue
(original residue number in PDB)		T270 M273 K371 R372 Y375 S376 G379 Y380 A381 N419 I420 K421 R445 R450 S453 V454 K456
Binding residue
(residue number reindexed from 1)		T86 M89 K181 R182 Y185 S186 G189 Y190 A191 N229 I230 K231 R255 R260 S263 V264 K266
Enzymatic activity
Enzyme Commision number 3.1.26.3: ribonuclease III.
Gene Ontology
Molecular Function
GO:0003725 double-stranded RNA binding
GO:0004525 ribonuclease III activity
Biological Process
GO:0006364 rRNA processing
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:5t16, PDBe:5t16, PDBj:5t16
PDBsum5t16
PubMed28111020
UniProtQ02555|RNT1_YEAST Ribonuclease 3 (Gene Name=RNT1)

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