Structure of PDB 6qnr Chain I8 Binding Site BS02

Receptor Information

>6qnr Chain I8 (length=84) Species: 300852 (Thermus thermophilus HB8)

AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNV
GMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPLA

Ligand information

>6qnr Chain 1H (length=2890)

ggucaagaugguaagggcccacgguggaugccucggcacccgagccgaug
aaggacguggcuaccugcgauaagccagggggagccgguagcgggcgugg
aucccuggauguccgaaugggggaacccggccggcgggaacgccggucac
cgcgcuuuuugcgcggggggaaccuggggaacugaaacaucucaguaccc
agaggagaggaaagagaaaucgacucccugaguagcggcgagcgaaaggg
gaccagccuaaaccguccggcuuguccgggcggggucguggggcccucgg
accgaauccccagccuagccgaagcuguugggaagcagcgccagagaggg
ugaaagccccguaggcgaaagguggggggauaggugaggguacccgagua
ccccgugguucguggagccaugggggaaucugggcggaccaccgccuaag
gcuaaguacuccgggugaccgauagcgcaccaguaccgugagggaaaggu
gaaaagaaccccgggaggggagugaaauagagccugaaaccgugggcuua
caagcagucacggccccgcaagggguuguggcgugccuauugaagcauga
gccggcgacucacggucgugggcgagcuuaagccguugaggcggaggcgu
agggaaaccgaguccgaacagggcgcaaacggccgaaaaguccgcggccg
uggacccgaaaccgggcgagcuagcccuggccagggugaagcugggguga
gacccaguggaggcccgaaccggugggggaugcaaaccccucggaugagc
uggggcuaggagugaaaagcuaaccgagcccggagauagcugguucuccc
cgaaaugacuuuagggucagccucaggcgcugacuggggccuguagagca
cugauagggcuagggggcccaccagccuaccaaacccugucaaacuccga
agggucccagguggagccugggagugagggcgcgagcgauaacguccgcg
uccgagcgcgggaacaaccgagaccgccagcuaaggcccccaagucuggg
cuaagugguaaaggauguggcgccgcgaagacagccaggauguuggagca
gccaucauuuaaagagugcguuagcucacuggucgaguggcgccgcgccg
aaaaugaucggggcuuaagcccagcgccgaagcugcgggucugggggaug
accccaggcgguaggggagcguucccgaugccgaugaaggccgacccgcg
agggcggcuggagguaagggaagugcgaaugccggcaugaguaacgauaa
agagggugagaaucccucucgccguaagcccaaggguuccuacgcaaugg
ucgucagcguaggguuaggcgggaccuaaggugaagccgaaaggcguagc
cgaagggcagccgguuaauauuccggcccuucccgcaggugcgauggggg
gacgcucuaggcuagggggaccggagccauggacgagcccggccagaagc
gcagggugggagguaggcaaauccgccucccaacaagcucugcguggugg
ggaagcccguacgggugacaaccccccgaagccagggagccaagaaaagc
cucuaagcacaaccugcgggaacccguaccgcaaaccgacacaggugggc
gggugcaagagcacucaggcgcgcgggagaacccucgccaaggaacucug
caaguuggccccguaacuucgggagaaggggugcucccuggggugaugag
ccccggggagccgcagugaacaggcucuggcgacuguuuaccaaaaacac
agcucucugcgaacucguaagaggagguauagggagcgacgcuugcccgg
ugccggaaggucaaggggaggggugcaagccccgaaccgaagccccggug
aacggcggccguaacuauaacgguccuaagguagcgaaauuccuugucgg
guaaguuccgaccugcacgaaaagcguaacgaccggagcgcugucucggc
gagggacccggugaaauugaacuggccgugaagaugcggccuacccgugg
caggacgaaaagaccccguggagcuuuacugcagccugguguuggcucuu
ggucgcgccugcguaggauaggugggagccugugaacccccgccuccggg
ugggggggaggcgccggugaaauaccacccuggcgcggcugggggccuaa
cccucggauggggggacagcgcuuggcgggcaguuugacuggggcggucg
ccuccuaaaagguaacggaggcgcccaaagguccccucaggcgggacgga
aauccgccggagagcgcaaggguagaagggggccugacugcgaggccugc
aagccgagcaggggcgaaagccgggccuagugaaccgguggucccgugug
gaagggccaucgaucaacggauaaaaguuaccccggggauaacaggcuga
ucucccccgagcguccacagcggcggggagguuuggcaccucgaugucgg
cucgucgcauccuggggcugaagaaggucccaaggguugggcuguucgcc
cauuaaagcggcacgcgagcuggguucagaacgucgugagacaguucggu
cucuauccgccacgggcgcaggaggcuugaggggggcucuuccuaguacg
agaggaccggaagggacgcaccucugguuucccagcugucccuccagggg
cauaagcuggguagccaugugcggaagggauaaccgcugaaagcaucuaa
gcgggaagcccgccccaagaugaggccucccacggcgucaagccgguaag
gacccgggaagaccacccgguggaugggccggggguguaagcgccgcgag
gcguugagccgaccggucccaaucguccgaggucuugacc

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..<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>....
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<<<<<.....>>>>>>.>>...<<<<<<.....<<....>>......>>>
>>.>.........<<....>>...<<<<<.....<<.....>>....>>>
>>...(((....<<<<<<<<.....>>>>>>>>......<<<<<<<<<..
<<<...<<<<<.<<<<.<<<...<<<<<......>>>>>((......<<<
.....))>>>...>>>...>>>>..>>>>>..>>>>>>>>>.>>>.....
<<<<<<<<<.......>>>>>>>>>......<<<<<..<<<<>>>>>..)
))......]].>>>>>>.]]...............<<....>>....]].
........<<<<....>>>>..................>>>>>>>>>>>.
......<<<<<<<<<<<....>>>>>>>>>>>...<............>.
<<<<<<....<<<<<<<<<<<<<..<<<...<<<.....>>>...>>>..
.<<....>>..<<<<.....>>>>.....<<..>>....>>>>>>>>>>>
>>..<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<....
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.>>>>>>>>....>>>>>><.<<<<<...<<<......<<<<<.<<<...
.>>>>>>>>...>>>..>>>>>..>.....>>>>>><......<<.....
<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<.
....>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>
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.<<<<<....>>>>>..>>>>..<<<<....<<<<<<<<.<<........
.<.....<<<<<...............>>>>><<<<<<<<<<<<.....>
>>>>>>>>>>>............<<<<<<<<<..<<<.........>>>.
.<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<<<..<
<<<<<<..<<<...<<...<<<<<....>>>>>...>>...>>>>>>>>.
.>>>>><<<<<<.......>>>>>>........<...........<<<<<
<.....>>>>>>.....>....>>>>>..>>.>>>>>>>..>..>>.>>>
>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<
<.(((.........<<<<.[[<<<<..<<<<<.<<<.<<<<<.<<<<<<<
<<<<<<<<<...........<<.<<..<<<.......<<<<<<<....>>
>>>>>....>>>............>>.>>..>>>>>>>>>>>>>>>>...
<<<<<....>>>>>....>>>>>.>>>..>>>>>..<<<<.....>>>><
<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.....
..>>>>>>.....<<...(((>>....>>>>>>>...<<<<..<<<....
..>>>..>>>>.<<<....>>>.>>))).......<<<<<<.(((..>>>
>..)))>>>>>>.............>>>>..]]>>>>.......<<<<..
.<<<<<<<..<<.......>>>..>>>>>>....>>>.>.......<<<<
<.<<<<<<..<<<<<<<<<......>>>>>>>..>>.<<<<<.....>>>
>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>...
.....)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<.......
........>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<))))>>>>
>>...>>>>>...>>>>.>>>>>...<<<....<<<<<...........>
>>>>....>>>.>>>>.......>>>>>>>..<<<<.....>>>>....<
<<<<<<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>
>>>>...>>>..>>>>>.>>>...>>>>....>>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6qnr Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction.
• Resolution: 3.1 Å
• Binding residue (original residue number in PDB): A2 H3 K4 K5 T10 N12 R14 D15 S16 Q17 A18 K19 R20 K24 R25 Y26 E27 Q29 R32 A33 G34 N35 I36 R39 R41 G42 T43 R44 G54 R55 D56 F57 T58 F60 F69 R77
• Binding residue (residue number reindexed from 1): A1 H2 K3 K4 T9 N11 R13 D14 S15 Q16 A17 K18 R19 K23 R24 Y25 E26 Q28 R31 A32 G33 N34 I35 R38 R40 G41 T42 R43 G53 R54 D55 F56 T57 F59 F68 R76

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6qnr, PDBe:6qnr, PDBj:6qnr
• PDBsum: 6qnr
• PubMed: 31175275
• UniProt: P60493|RL27_THET8 Large ribosomal subunit protein bL27 (Gene Name=rpmA)