Structure of PDB 8w09 Chain I Binding Site BS02

Receptor Information
>8w09 Chain I (length=260) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAM
HGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYF
LLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGV
IESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERI
VDIIATDIQTKELQKQITKIQNFRVYYRGPAKLLWKGEGAVVIQDNSDIK
VVPRRKAKII
Ligand information
Receptor-Ligand Complex Structure
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PDB8w09 HIV-1 integrase assembles multiple species of stable synaptic complex intasomes that are active for concerted DNA integration in vitro.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
A49 M50 H51
Binding residue
(residue number reindexed from 1)
A49 M50 H51
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function

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Biological Process
External links
PDB RCSB:8w09, PDBe:8w09, PDBj:8w09
PDBsum8w09
PubMed38582148
UniProtP12497|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol)

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