Structure of PDB 8u5h Chain I Binding Site BS02

Receptor Information
>8u5h Chain I (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQRS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
Ligand information
>8u5h Chain H (length=157) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caggatgtatatatctgacacgtgcctggagactagggagtaatcccctt
ggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgctag
agctgtctacgaccaattgagcggcctcggcaccgggattctccaggatg
tttacgt
Receptor-Ligand Complex Structure
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PDB8u5h Cryo-EM structure of human DNMT3A N-terminal domain bound to H2AK119Ub nucleosome
Resolution3.23 Å
Binding residue
(original residue number in PDB)
R40 R42 T45 R72 R83 F84 Q85 R86 R116 V117 T118
Binding residue
(residue number reindexed from 1)
R3 R5 T8 R35 R46 F47 Q48 R49 R79 V80 T81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8u5h, PDBe:8u5h, PDBj:8u5h
PDBsum8u5h
PubMed
UniProtP02302|H3C_XENLA Histone H3.3C (Gene Name=h3-5)

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