Structure of PDB 8siy Chain I Binding Site BS02

Receptor Information
>8siy Chain I (length=107) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTA
EILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPN
IQSVLLP
Ligand information
>8siy Chain L (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aggatgtatatatctgacacgtgcctggagactagggagtaatccccttg
gcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgctaga
gctgtctacgaccaattgagcggcctcggcaccgggattctccagga
Receptor-Ligand Complex Structure
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PDB8siy A dual role for the chromatin reader ORCA/LRWD1 in targeting the origin recognition complex to chromatin.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
R11 K15 R17 R32 R77
Binding residue
(residue number reindexed from 1)
R1 K5 R7 R22 R67
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8siy, PDBe:8siy, PDBj:8siy
PDBsum8siy
PubMed37551430
UniProtP06897|H2A1_XENLA Histone H2A type 1

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