Structure of PDB 8jke Chain I Binding Site BS02

Receptor Information
>8jke Chain I (length=254) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AEEEESGALRFGVLGPVRAWRDGETLATGSPQQRALLAALLLREGRTATA
GELIDALWGEEPPSQALAAVRTYASRLRKVLDPGVLVSESGGYAVRGLAE
GALDLARAQDLASAAEKARSAGDLCHARDLLRRALDLWDGEVLAGVPGPY
AQTQRVRLGEWRLQLLETRLDMDLDQGCHAEAVSELTALTAAHPLRERLR
ELLMLALYRSGRQAEALAVYADTRRLLADELGVDPRPGLQELQQRILQAD
PALA
Ligand information
>8jke Chain P (length=61) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tgcgacggtctgacgctctacacagtgccagggggagataaacgaacgct
gaacgctccgg
Receptor-Ligand Complex Structure
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PDB8jke Structural and functional characterization of AfsR, a SARP family transcriptional activator of antibiotic biosynthesis in Streptomyces
Resolution3.67 Å
Binding residue
(original residue number in PDB)		R87 R92 R94 Y109
Binding residue
(residue number reindexed from 1)		R71 R76 R78 Y93
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0031409 pigment binding
GO:0043531 ADP binding
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0006355 regulation of DNA-templated transcription
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8jke, PDBe:8jke, PDBj:8jke
PDBsum8jke
PubMed38427710
UniProtP25941|AFSR_STRCO Regulatory protein AfsR (Gene Name=afsR)

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