Structure of PDB 8it1 Chain I Binding Site BS02

Receptor Information
>8it1 Chain I (length=465) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGL
QIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEITDEE
IRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPEEIYKY
CRPNSVLYNYDAQFHDQLKARLLEHTIPTQILRESTLAWRDFKNTFGAPI
RDFSKIEGHLAWTISTAAYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSK
NPQNACCAAQMFLDNGDGTVFKGEVGPWYNPEKGEYHLKPKEAKALLTQA
LESYKEQNKSYPKEVFIHARTRFNDEEWNAFNEVTPKNTNLVGVTITKSK
PLKLYKTEGAFPIMRGNAYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIF
IEINKGEAEIQQVLKDILALTKLNYNACIYADGEPVTLRFANKIGEILTA
STEIKTPPLAFKYYI
Ligand information
>8it1 Chain L (length=21) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugagguaguagguuguauagu
.....................
Receptor-Ligand Complex Structure
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PDB8it1 Nucleic acid-triggered NADase activation of a short prokaryotic Argonaute.
Resolution3.41 Å
Binding residue
(original residue number in PDB)		E327 L423 S434 M435 N439
Binding residue
(residue number reindexed from 1)		E285 L381 S392 M393 N397
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8it1, PDBe:8it1, PDBj:8it1
PDBsum8it1
PubMed37783228
UniProtA0A1I7NFD7

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