Structure of PDB 8c8h Chain I Binding Site BS02

Receptor Information
>8c8h Chain I (length=669) Species: 502057 (Vaccinia virus GLV-1h68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DEMTYNLYDLFFNTLDMYLRQKKISILVNDDVVIVSYKEIKKIPFNMKNL
LPYLEKNLDQLRFSKKYLDFAYLCRHIGIPISKKKYNVRYVFLYKIDGLS
IPIIIKDFLDVKYVYLENTGKIYKNSFSEDHNNSLSDWGKVIIPLLKDRH
LYSYIFLSSYHLHSYYTDLIARDEPVFVKRKKLDIIEIDEPEAWKRDVRV
EFAPCEHQIRLKEAMKVDANYFTKINNFANEFIYYEDGVAYCRVCGINIP
IFNLDAADVIKNTVIVSTFNKTIFLSEPYSYFVHSQRFIFNIIMSFDNIM
KSQTWVMKYNINRLILNFLIDINSRRQEYEKKFSSEIKRGLFFLRLSANL
FETELFYVSKMLNLNYIVALVIILNSSADFIVSYMTSKNKTVEESTLKYA
ISVVIYDFLVKTRICEKGSLDTIVLFTDVYTSIMPEELDLHFQRITLELR
KLVSIQRSALEPNYDVESRGEELPLSALKFFDTSTIIVKTMAPVHTCVEQ
KIVAPTPSVEPTDASLKNFKELTCDEDIKILIRVHDTNATKLVIFPSHLK
IEIERKKLIIPLKSLYITNTLKYYYSNSYLYVFRFGDPMPFEEELIDHEH
VQYKINCYNILRYHLLPDSDVFVYFSNSLNREALEYAFYIFLSKYVNVKQ
WIDENITRIKELYMINFNN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8c8h Chain I Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8c8h Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.
Resolution3.84 Å
Binding residue
(original residue number in PDB)		H328 C363 C366
Binding residue
(residue number reindexed from 1)		H207 C242 C245
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006353 DNA-templated transcription termination
GO:0006355 regulation of DNA-templated transcription
GO:0039695 DNA-templated viral transcription
Cellular Component
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8c8h, PDBe:8c8h, PDBj:8c8h
PDBsum8c8h
PubMed
UniProtP68438|RAP94_VACCW RNA polymerase-associated transcription-specificity factor RAP94 (Gene Name=OPG109)

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