Structure of PDB 7zmb Chain I Binding Site BS02

Receptor Information
>7zmb Chain I (length=185) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATPAGPPPKNFRLPPPKNWDEESESTIDKVGKYFLMTEMLRGMYVLLEQF
FRPPYTIYYPFEKGPISPRFRGEHALRRYPSGEERCIACKLCEAVCPAQA
ITIEAEERADGSRRTTRYDIDMTKCIYCGFCQESCPVDAIVESPNAEYAT
ETREELLYNKEKLLANGDKWEPELAAAIRADAPYR
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7zmb Chain I Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7zmb Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Resolution2.75 Å
Binding residue
(original residue number in PDB)		H112 C134 P135 I139 C163 I164 Y165 C166 G167 C169 E180
Binding residue
(residue number reindexed from 1)		H74 C96 P97 I101 C125 I126 Y127 C128 G129 C131 E142
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0051539 4 iron, 4 sulfur cluster binding
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:7zmb, PDBe:7zmb, PDBj:7zmb
PDBsum7zmb
PubMed36427319
UniProtG0SBG8

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