Structure of PDB 7uy5 Chain I Binding Site BS02

Receptor Information
>7uy5 Chain I (length=528) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNLKILEDVKKLYLQSFDYIKNGISSITFLYKFISVNPTLLLINEKTQAK
RRIFQGEYLYGKKKIQFNIIAKNLEIERELIQFFKKPYQCYIMHNVQVFQ
LYYLIDESSHVLEDDSMDFISTLTRLSDSFNSNEFVFETNYSIQISQMPK
PLNTTHFKLLQPKVVNSFEGVILQVQEGKNILQIEELIDQVYLNSRRDRF
YILKVANGKNYMDFIEVYLVYDNEDQEAKQQLQFYLKPFQRILIFQSLKH
FTKNLKLFMISFFYSSGVQPNNSNVKNFLVSHKGVEFFSRFDIQKNELLC
KDLIKSYNKLPLSNISKLLEDEGVMIRSNMKFQVRVKKVKYFKIRLNCLN
CKQEWTVGLKNCINCKGQQSYISYNIQVLVQDQHFLEQQAYIYLYDDLAA
QFFNITESEKKELHLHLTKNETFIQLYYSFNKDYPLSIIKFKDKIFNKDI
TNCIVAYPFADIDNKIKQQIFVNGTYISTNYSQGQKICLKPIPCLKVMYV
FPQEDIKLSALKIIEEINQLKIQIDQLN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7uy5 Chain I Residue 900 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7uy5 Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		C398 C412
Binding residue
(residue number reindexed from 1)		C348 C362
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005694 chromosome
GO:0005697 telomerase holoenzyme complex

View graph for
Cellular Component
External links
PDB RCSB:7uy5, PDBe:7uy5, PDBj:7uy5
PDBsum7uy5
PubMed35831498
UniProtA0PGB2|TAP75_TETTS Telomerase-associated protein of 75 kDa (Gene Name=TAP75)

[Back to BioLiP]