Structure of PDB 6rwn Chain I Binding Site BS02

Receptor Information
>6rwn Chain I (length=270) Species: 11723 (Simian immunodeficiency virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GFLDGIEKAQEEHEKYHNNWRAMAEDFQIPQVVAKEIVAQCPKCQVKGEA
MHGQVDASPKTWQMDCTHLEGKVIIVAVHVASGYIEAEVLPAETGKETAH
FLLKLAARWPVKHLHTDNGDNFTSSAVQAVCWWAQIEHTFGVPYNPQSQG
VVESMNHQLKTIITQIRDQAEKIETAVQMAVLIHNFKRKGGIGGYSAGER
IIDIIASDLQTTKLQNQISKIQNFRVYFREGRDQQWKGPATLIWKGEGAV
VIQDGQDLKVVPRRKCKIIK
Ligand information
Receptor-Ligand Complex Structure
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PDB6rwn Structural basis of second-generation HIV integrase inhibitor action and viral resistance.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		E152 H156
Binding residue
(residue number reindexed from 1)		E153 H157
Enzymatic activity
Enzyme Commision number 3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:6rwn, PDBe:6rwn, PDBj:6rwn
PDBsum6rwn
PubMed32001525
UniProtE1ANT8

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