Structure of PDB 6rau Chain I Binding Site BS02

Receptor Information
>6rau Chain I (length=432) Species: 1219 (Prochlorococcus marinus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFG
VKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATK
EEWNGFYRRVLIKDLRCGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANH
EKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIEN
VLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPL
ENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQK
RFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSV
EEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLG
QLVEIRADAKTKSKDGVAFSLRFPRFKCFRGF
Ligand information
Receptor-Ligand Complex Structure
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PDB6rau Structural intermediates of a DNA-ligase complex illuminate the role of the catalytic metal ion and mechanism of phosphodiester bond formation.
Resolution1.99 Å
Binding residue
(original residue number in PDB)		S20 R21 L22 G54 K56 I57 V171 R172 S186 R187 K190 F226 M230 H234 K340 K342 S385 F387 S388 D389 F427 R429
Binding residue
(residue number reindexed from 1)		S16 R17 L18 G50 K52 I53 V167 R168 S182 R183 K186 F222 M226 H230 K336 K338 S381 F383 S384 D385 F423 R425
Enzymatic activity
Enzyme Commision number 6.5.1.1: DNA ligase (ATP).
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003909 DNA ligase activity
GO:0003910 DNA ligase (ATP) activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6rau, PDBe:6rau, PDBj:6rau
PDBsum6rau
PubMed31312841
UniProtA0A0A2ACP7

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