Structure of PDB 6ras Chain I Binding Site BS02

Receptor Information
>6ras Chain I (length=433) Species: 74545 (Prochlorococcus marinus str. MIT 9302) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFG
VKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATK
EEWNGFYRRVLIKDLACGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANH
EKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIEN
VLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPL
ENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQK
RFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSV
EEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLG
QLVEIRADAKTKSKDGVAFSLRFPRFKCFRGFK
Ligand information
Receptor-Ligand Complex Structure
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PDB6ras Structural intermediates of a DNA-ligase complex illuminate the role of the catalytic metal ion and mechanism of phosphodiester bond formation.
Resolution2.75 Å
Binding residue
(original residue number in PDB)		G54 K56 G170 V171 R172 S186 R187 N188 K190 F226 H234 F427
Binding residue
(residue number reindexed from 1)		G50 K52 G166 V167 R168 S182 R183 N184 K186 F222 H230 F423
Enzymatic activity
Enzyme Commision number 6.5.1.1: DNA ligase (ATP).
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003909 DNA ligase activity
GO:0003910 DNA ligase (ATP) activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6ras, PDBe:6ras, PDBj:6ras
PDBsum6ras
PubMed31312841
UniProtA0A0A2ACP7

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