Structure of PDB 6b6h Chain I Binding Site BS02

Receptor Information
>6b6h Chain I (length=75) Species: 83334 (Escherichia coli O157:H7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKS
LTEIKDVLASRGLSLGMRLENWPPA
Ligand information
>6b6h Chain 2 (length=88) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgccgcgtcagactcgtaggattatagcatacgtgaggtgggatgtcaag
gccttttttgcctaaaatgtgatctagatcacatttta
Receptor-Ligand Complex Structure
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PDB6b6h Structural basis of bacterial transcription activation.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		N294 L295 G296 K298
Binding residue
(residue number reindexed from 1)		N45 L46 G47 K49
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6b6h, PDBe:6b6h, PDBj:6b6h
PDBsum6b6h
PubMed29146813
UniProtP0A7Z4|RPOA_ECOLI DNA-directed RNA polymerase subunit alpha (Gene Name=rpoA)

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