Structure of PDB 5wsg Chain I Binding Site BS02

Receptor Information
>5wsg Chain I (length=102) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGGISYDQLAKLSYEKTLRNLATQTQNSSKQDKVQKDTKTGKITIADDDK
LVNKLAVSLQSESKKRYEARKRQMQNAKTLYGVESFINDKNKQFNEKLSR
ES
Ligand information
>5wsg Chain L (length=91) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acgaaucucuuugccuuuuggcuuagaucaaguguaguaucuguucuuuu
caacauuuuuuggcaccgcgacccucgcacuuguggagucg
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Receptor-Ligand Complex Structure
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PDB5wsg Structure of a yeast step II catalytically activated spliceosome
Resolution4.0 Å
Binding residue
(original residue number in PDB)		R92 G93 T114 K174 R179 Q202 F203 K206 R209
Binding residue
(residue number reindexed from 1)		R1 G2 T23 K65 R70 Q93 F94 K97 R100
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000384 first spliceosomal transesterification activity
GO:0000386 second spliceosomal transesterification activity
GO:0005515 protein binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005829 cytosol
GO:0071004 U2-type prespliceosome
GO:0071006 U2-type catalytic step 1 spliceosome
GO:0071007 U2-type catalytic step 2 spliceosome
GO:0071008 U2-type post-mRNA release spliceosomal complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:5wsg, PDBe:5wsg, PDBj:5wsg
PDBsum5wsg
PubMed27980089
UniProtP53277|SYF2_YEAST Pre-mRNA-splicing factor SYF2 (Gene Name=SYF2)

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