Structure of PDB 3kov Chain I Binding Site BS02

Receptor Information
>3kov Chain I (length=90) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSS
NKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKK
Ligand information
Receptor-Ligand Complex Structure
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PDB3kov Structure of the MADS-box/MEF2 Domain of MEF2A Bound to DNA and Its Implication for Myocardin Recruitment.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		G2 R3 I6 K23 R24 K30
Binding residue
(residue number reindexed from 1)		G1 R2 I5 K22 R23 K29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:3kov, PDBe:3kov, PDBj:3kov
PDBsum3kov
PubMed20132824
UniProtQ02078|MEF2A_HUMAN Myocyte-specific enhancer factor 2A (Gene Name=MEF2A)

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