Structure of PDB 8ipa Chain HB Binding Site BS02

Receptor Information
>8ipa Chain HB (length=205) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRRPARCYRQIKNKPYPKSRYCRGVPDPKIRIYDVGMKKKGVDEFPSCVH
LVSWEKENVSSEALEAARIACNKYMTKNAGKDAFHLRVRVHPYHVLRINK
QTGMRGAFGKPLGTCARVDIGQVLLSVRCKESNAVHADEALRRAKFKFPG
RQKIIRSRKWGFTKFNRADYIKYKSEGRIVPDGVNAKLLGVHGPIAKRAP
GQAIL
Ligand information
>8ipa Chain TB (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggaugcgaucauaccagcacuaaggcaucggaucccgucagaacuccgaa
guuaagcgugcuugggcgagaguaguacaaggaugggugaccucuuggga
aguccucguguugcauuccc
<<<<<<<<<....<<<<<<<......<<<<<..............>>>..
>>.....>>>>>.>><<<<<.<.....<.<<<<.<<....>>>>>>.>..
..>.>>>>>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB8ipa Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		E56 G201 V202 H203 G204 P205 I206 R209 I215
Binding residue
(residue number reindexed from 1)		E55 G190 V191 H192 G193 P194 I195 R198 I204
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ipa, PDBe:8ipa, PDBj:8ipa
PDBsum8ipa
PubMed38267667
UniProtA0A3B6HUM3

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