Structure of PDB 8ipb Chain HA Binding Site BS02

Receptor Information

>8ipb Chain HA (length=203) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GAYKFVSELWRRKQSDVMRFVQRVRCWEYRQQPAIVRITRPTRPDRARRL
GFKAKQGYVVYRIRVRRGGRKRPVPKGIVYGKPKHQGITQLKFQRNKRSV
AEERAGRRLGGLRVLNSYWVNEDSTYKYFEVILVDVAHSAVRNDPRINWL
CKPVHKHRELRGLTSAGKKFRGLRGKGHRHHKNRPSRRATWKRNQTVSLR
RYR

Ligand information

>8ipb Chain SB (length=160) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cgacucucggcaacggauaucucggcucucgcaucgaugaagaacguagc
gaaaugcgauaccuggugugaauugcagaaucccgugaaccaucgagucu
uugaacgcaaguugcgcccgaggccauccggccgagggcacgccugccug
ggcgucacgc

.........................................<<<<<<.((
.....>>>....<<<<<<<.....))............>.>>>>.>>..>
>>....<<.....>><<<<..<<<<....>>>>..>>>>...........
..........

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8ipb Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Resolution	3.4 Å
Binding residue (original residue number in PDB)	R38 Q57 V60 Y62 D136 H139
Binding residue (residue number reindexed from 1)	R37 Q56 V59 Y61 D135 H138

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:8ipb, PDBe:8ipb, PDBj:8ipb
PDBsum	8ipb
PubMed	38267667
UniProt	W5FEX7

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