Structure of PDB 4wu1 Chain H8 Binding Site BS02

Receptor Information

>4wu1 Chain H8 (length=175) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQ
ASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYV
PLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSL
HASDLKLPPGVELAVSPEETIAAVV

Ligand information

>4wu1 Chain 16 (length=122) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aaucccccgugcccauagcggcguggaaccacccguucccauuccgaaca
cggaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccugg
gagaguaggucggugcggggga

...<<<<<<<<<<....<<<<<<<<....<<<<<<...............
>>>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>
.......>>>.>>>>>>>>>>.

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4wu1 Structural insights into the translational infidelity mechanism.
Resolution	3.2 Å
Binding residue (original residue number in PDB)	R10 R19 V27 Y29 N30 R31 N34 R72 Q73 E84 H85 V165
Binding residue (residue number reindexed from 1)	R10 R19 V27 Y29 N30 R31 N34 R72 Q73 E84 H85 V165

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0008097	5S rRNA binding
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:4wu1, PDBe:4wu1, PDBj:4wu1
PDBsum	4wu1
PubMed	26037619
UniProt	Q5SHZ1\|RL25_THET8 Large ribosomal subunit protein bL25 (Gene Name=rplY)

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