Structure of PDB 8g88 Chain H Binding Site BS02

Receptor Information
>8g88 Chain H (length=94) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Ligand information
>8g88 Chain J (length=168) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcatatgctaatgtgtgcatgtgtgtgactatgtgcgcatgcatgtgcat
gtgtgtgcatatacgtgtgtgcatgcatgtgcatatatgtgtgcacgtgt
gtgtgcatgtgtgtgtatgtgtatatattaacctgtgtgcattgtgtgca
tatattagcatgtgtgca
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8g88 Histone modifications regulate pioneer transcription factor cooperativity.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		T29 Y39 I51 S53 R83 S84 T85
Binding residue
(residue number reindexed from 1)		T1 Y11 I23 S25 R55 S56 T57
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8g88, PDBe:8g88, PDBj:8g88
PDBsum8g88
PubMed37225990
UniProtP02281|H2B11_XENLA Histone H2B 1.1

[Back to BioLiP]