Structure of PDB 8dw6 Chain H Binding Site BS02

Receptor Information
>8dw6 Chain H (length=322) Species: 2681598 (Escherichia phage T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIPWIDNEFAYRALAHLPKFTQVNNSSTFKLRFRCPVCGDSKTDQNKARG
WYYGDNNEGNIHCYNCNYHAPIGIYLKEFEPDLYREYIFEIRKEKKKIIK
SLPSCVRLDKLAEDHPIIKYVKARCIPKDKWKYLWFTTEWPKLVNSIAPG
TYKKEISEPRLVIPIYNANGKAESFQGRALKKDAPQKYITIEAYPEATKI
YGVERVKDGDVYVLEGPIDSLFIENGIAITGGQLDLEVVPFKDRRVWVLD
NEPRHPDTIKRMTKLVDAGERVMFWDKSPWKSKDVNDMIRKEGATPEQIM
EYMKNNIAQGLMAKMRLSKYAK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8dw6 Chain H Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8dw6 Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		C37 C40 C65 C68
Binding residue
(residue number reindexed from 1)		C35 C38 C63 C66
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0003896 DNA primase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0039693 viral DNA genome replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8dw6, PDBe:8dw6, PDBj:8dw6
PDBsum8dw6
PubMed37474605
UniProtP04520|PRIM_BPT4 DNA primase (Gene Name=61)

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