Structure of PDB 7y74 Chain H Binding Site BS02

Receptor Information

>7y74 Chain H (length=170) Species: 307972 (Apostichopus japonicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PSQVRQNFHELCEAGVNKQINLELYASYTYHSIAFYFDRDDVALPGAHKY
FKKQSEEEREHAEKLMKFQNQRGGRVKLKDITAPEKEEWGSLLDAFKVAL
ELEKKVNQSLLDLHGLADSKKDAQMCAFIATHYLTEQVEAIKEIGDHITN
LKRVGTGLGEFIYDKENLKE

Ligand information

Ligand ID

InChI

InChI=1S/Fe/q+3

InChIKey

VTLYFUHAOXGGBS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Fe+3]

Formula

Name

FE (III) ION

PDB chain

7y74 Chain H Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7y74 Apostichopus japonicus ferritin mutant-D129A/E132A
Resolution	1.98 Å
Binding residue (original residue number in PDB)	E60 E105 Q139
Binding residue (residue number reindexed from 1)	E58 E103 Q137
Annotation score	5

Enzymatic activity

Enzyme Commision number

1.16.3.1: ferroxidase.

Gene Ontology

	Molecular Function
GO:0004322	ferroxidase activity
GO:0008198	ferrous iron binding
GO:0008199	ferric iron binding
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006826	iron ion transport
GO:0006879	intracellular iron ion homeostasis
GO:0006880	intracellular sequestering of iron ion

	Cellular Component
GO:0005737	cytoplasm

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External links

PDB	RCSB:7y74, PDBe:7y74, PDBj:7y74
PDBsum	7y74
PubMed
UniProt	Q2QJV4

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