Structure of PDB 7xpx Chain H Binding Site BS02

Receptor Information
>7xpx Chain H (length=96) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RRKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEAS
RLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA
Ligand information
>7xpx Chain J (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcacaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacggattccgtacgtgcgtttaagcggtgctag
agctgtctacgaccaattgagcggcctcggcaccgggattgtgat
Receptor-Ligand Complex Structure
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PDB7xpx Structural basis of nucleosomal H4K20 methylation by methyltransferase SET8.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
K28 K31 I36 Y37
Binding residue
(residue number reindexed from 1)
K3 K6 I11 Y12
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:7xpx, PDBe:7xpx, PDBj:7xpx
PDBsum7xpx
PubMed35532550
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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