Structure of PDB 7k78 Chain H Binding Site BS02

Receptor Information
>7k78 Chain H (length=93) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIATEASKLAA
YNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSST
Ligand information
>7k78 Chain J (length=116) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tatttcttttttaactttcggaaatcaaatacactaatattttaaatttt
attttttaaaaataaactactttttattttttactttttttaaaaatata
ataaaatcaaatatca
Receptor-Ligand Complex Structure
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PDB7k78 Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R37 Y46 S59 K90 S91 T92
Binding residue
(residue number reindexed from 1)		R1 Y10 S23 K54 S55 T56
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006301 postreplication repair
GO:0006325 chromatin organization
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0031298 replication fork protection complex
GO:0032991 protein-containing complex

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Cellular Component
External links
PDB RCSB:7k78, PDBe:7k78, PDBj:7k78
PDBsum7k78
PubMed33741944
UniProtP02293|H2B1_YEAST Histone H2B.1 (Gene Name=HTB1)

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