Structure of PDB 5zct Chain H Binding Site BS02

Receptor Information

>5zct Chain H (length=292) Species: 83333 (Escherichia coli K-12)

MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHY
KGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDK
LRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIG
VVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAA
IERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTMALDVAGVDIL
RANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATT

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 5zct Chain H Residue 402

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5zct Structural polymorphism of the Escherichia coli poly-alpha-L-glutamate synthetase RimK
• Resolution: 2.05 Å
• Binding residue (original residue number in PDB): D248 E260
• Binding residue (residue number reindexed from 1): D248 E260
• Annotation score: 4

Enzymatic activity

• Enzyme Commision number: 6.3.2.-

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0005524 ATP binding
• GO:0016874 ligase activity
• GO:0018169 ribosomal S6-glutamic acid ligase activity
• GO:0042802 identical protein binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation
• GO:0009432 SOS response
• GO:0018410 C-terminal protein amino acid modification
• GO:0036211 protein modification process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:5zct, PDBe:5zct, PDBj:5zct
• PDBsum: 5zct
• PubMed: 29969101
• UniProt: P0C0U4|RIMK_ECOLI Ribosomal protein bS6--L-glutamate ligase (Gene Name=rimK)