Structure of PDB 5pab Chain H Binding Site BS02
Receptor Information
>5pab Chain H (length=248) Species:
9606
(Homo sapiens) [
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IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWR
NLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPV
VLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNV
PRLMTQDCLQQSRNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYL
TGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
Ligand information
Ligand ID
CA
InChI
InChI=1S/Ca/q+2
InChIKey
BHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
Formula
Ca
Name
CALCIUM ION
ChEMBL
DrugBank
DB14577
ZINC
PDB chain
5pab Chain H Residue 306 [
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Receptor-Ligand Complex Structure
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PDB
5pab
Crystal Structure of a Factor VIIa complex
Resolution
1.99 Å
Binding residue
(original residue number in PDB)
E58 D60 E63 E68
Binding residue
(residue number reindexed from 1)
E58 D60 E63 E68
Annotation score
4
Enzymatic activity
Enzyme Commision number
3.4.21.21
: coagulation factor VIIa.
Gene Ontology
Molecular Function
GO:0004252
serine-type endopeptidase activity
Biological Process
GO:0006508
proteolysis
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Molecular Function
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Biological Process
External links
PDB
RCSB:5pab
,
PDBe:5pab
,
PDBj:5pab
PDBsum
5pab
PubMed
UniProt
P08709
|FA7_HUMAN Coagulation factor VII (Gene Name=F7)
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