Structure of PDB 6hcj Chain G2 Binding Site BS02

Receptor Information

>6hcj Chain G2 (length=185) Species: 9986 (Oryctolagus cuniculus)

TPDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRK
AQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLV
NAIINSGPREDSTRIRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTI
AECLADELINAAKGSSNSYAIKKKDELERVAKSNR

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 6hcj Chain G2 Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6hcj ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
• Resolution: 3.8 Å
• Binding residue (original residue number in PDB): A162 F163 R164 N165
• Binding residue (residue number reindexed from 1): A143 F144 R145 N146
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003729 mRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0000028 ribosomal small subunit assembly
• GO:0006412 translation

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:0022626 cytosolic ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6hcj, PDBe:6hcj, PDBj:6hcj
• PDBsum: 6hcj
• PubMed: 30293783
• UniProt: G1TFM5|RS5_RABIT Small ribosomal subunit protein uS7 (Gene Name=RPS5)