Structure of PDB 8tpl Chain G Binding Site BS02

Receptor Information
>8tpl Chain G (length=419) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPFSDFVLALKDNPYFGAGFGLVGVGTALAMARKGAQLGLVAFRRHYMIT
LEVPARDRSYAWLLSWLTRHSTRTQHLSVETSYLQHESGRISTKFEFIPS
PGNHFIWYQGKWIRVERNRDMQMVDLQTGTPWESVTFTALGTDRKVFFNI
LEEARALALQQEEGKTVMYTAVGSEWRTFGYPRRRRPLDSVVLQQGLADR
IVKDIREFIDNPKWYIDRGIPYRRGYLLYGPPGCGKSSFITALAGELEHS
ICLLSLTDSSLSDDRLNHLLSVAPQQSLVLLEDVDAAFLSRDLAVENPIK
YQGLGRLTFSGLLNALDGVASTEARIVFMTTNYIDRLDPALIRPGRVDLK
EYVGYCSHWQLTQMFQRFYPGQAPSLAENFAEHVLKATSEISPAQVQGYF
MLYKNDPMGAVHNIESLRP
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8tpl Chain G Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8tpl Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Resolution3.46 Å
Binding residue
(original residue number in PDB)		K236 S237
Binding residue
(residue number reindexed from 1)		K236 S237
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008566 mitochondrial protein-transporting ATPase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0007005 mitochondrion organization
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0033617 mitochondrial cytochrome c oxidase assembly
GO:0034551 mitochondrial respiratory chain complex III assembly
GO:0071806 protein transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8tpl, PDBe:8tpl, PDBj:8tpl
PDBsum8tpl
PubMed38821922
UniProtQ9CZP5|BCS1_MOUSE Mitochondrial chaperone BCS1 (Gene Name=Bcs1l)

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