Structure of PDB 8sr2 Chain G Binding Site BS02

Receptor Information
>8sr2 Chain G (length=236) Species: 243233 (Methylococcus capsulatus str. Bath) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLDKKWLTFALAIYTVFYLWVRWYEGVYGWSAGLDSFAPEFETYWMNFLY
TEIVLEIVTASILWGYLWKTRDRNLAALTPREELRRNFTHLVWLVAYAWA
IYWGASYFTEQDGTWHQTIVRDTDFTPSHIIEFYLSYPIYIITGFAAFIY
AKTRLPFFAKGISLPYLVLVVGPFMILPNVGLNEWGHTFWFMEELFVAPL
HYGFVIFGWLALAVMGTLTQTFYSFAQGGLGQSLCE
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain8sr2 Chain G Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8sr2 Product analogue binding identifies the copper active site of particulate methane monooyxgenase
Resolution2.36 Å
Binding residue
(original residue number in PDB)		D156 H160 H173
Binding residue
(residue number reindexed from 1)		D112 H116 H129
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.13.25: methane monooxygenase (soluble).
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0015049 methane monooxygenase [NAD(P)H] activity
GO:0046872 metal ion binding
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:8sr2, PDBe:8sr2, PDBj:8sr2
PDBsum8sr2
PubMed
UniProtQ603F1

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