Structure of PDB 8scb Chain G Binding Site BS02

Receptor Information
>8scb Chain G (length=218) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPP
AINQFTQVLDRQTATQLLKLAHKYRPETKQEKKQRLLARAERPPVLRAGV
NTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCILKGKARL
GRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGN
VLGPKSVARIAKLEKAKA
Ligand information
>8scb Chain 8 (length=156) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu
.........................................<<<<<<<<<
....>>>>.....<.<<<......>>.............>>>..>...>>
>....<<<..>>><<<<<<<<.......>>>>>>>>..............
......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8scb Structure and consequences of eRF1 glued to the ribosomal decoding center
Resolution2.5 Å
Binding residue
(original residue number in PDB)		T52 W57 Y60 I61 Q64 R65 R89 H159 D160 K185 R189
Binding residue
(residue number reindexed from 1)		T24 W29 Y32 I33 Q36 R37 R61 H119 D120 K145 R149
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000470 maturation of LSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8scb, PDBe:8scb, PDBj:8scb
PDBsum8scb
PubMed38172604
UniProtG1STW0|RL7A_RABIT Large ribosomal subunit protein eL8 (Gene Name=RPL7A)

[Back to BioLiP]