Structure of PDB 8rjb Chain G Binding Site BS02

Receptor Information

>8rjb Chain G (length=233) Species: 9986 (Oryctolagus cuniculus)

VVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKV
PPAINQFTQVLDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAKRP
PVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCI
LKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEI
RRHWGGNVLGPKSVARIAKLEKAKAKELATKLG

Ligand information

>8rjb Chain v (length=156)

cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu

.........................................<<<<<<<<<
....>>>>.....<.<<<......>>.............>>>..>...>>
>....<<....>><<<<<<<<<.....>>>>>>>>>..............
......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8rjb UCSF ChimeraX: Meeting modern challenges in visualization and analysis.
• Resolution: 2.69243 Å
• Binding residue (original residue number in PDB): T105 W110 Y113 I114 Q117 R118 R142 H212 D213 K238 R242
• Binding residue (residue number reindexed from 1): T26 W31 Y34 I35 Q38 R39 R63 H126 D127 K152 R156

Gene Ontology

Molecular Function

• GO:0003723 RNA binding

Biological Process

• GO:0000470 maturation of LSU-rRNA
• GO:0042254 ribosome biogenesis

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8rjb, PDBe:8rjb, PDBj:8rjb
• PDBsum: 8rjb
• PubMed: 38896445
• UniProt: G1STW0|RL7A_RABIT Large ribosomal subunit protein eL8 (Gene Name=RPL7A)