Structure of PDB 8qfd Chain G Binding Site BS02

Receptor Information
>8qfd Chain G (length=214) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPP
AINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARRPPVLRAGVNT
VTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGR
LVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVL
GPKSVARIAKLEKA
Ligand information
>8qfd Chain 8 (length=144) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagcu
agcugcgagaauuaaugugaauugcaggcgaucaucgacacuucgaacgc
acuugcggccccgggcccggggcuacgccugucugagcgucgcu
........................................<<<<<<<<<.
...>>>>.....<.<<<......>>.......>>>..>...>>>....<<
....>><<<<<<<<<>>>>>>>>>....................
Receptor-Ligand Complex Structure
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PDB8qfd The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons
Resolution2.2 Å
Binding residue
(original residue number in PDB)		T52 Y60 I61 Q64 R65 R89 H159 K185 R189
Binding residue
(residue number reindexed from 1)		T24 Y32 I33 Q36 R37 R61 H117 K143 R147
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0045296 cadherin binding
Biological Process
GO:0000470 maturation of LSU-rRNA
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0045202 synapse
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qfd, PDBe:8qfd, PDBj:8qfd
PDBsum8qfd
PubMed38383789
UniProtP62424|RL7A_HUMAN Large ribosomal subunit protein eL8 (Gene Name=RPL7A)

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