Structure of PDB 8fk4 Chain G Binding Site BS02

Receptor Information
>8fk4 Chain G (length=828) Species: 1309 (Streptococcus mutans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKYNQVYDRSAQSFEHVDHYLTAESWYRPKYILKDGKTWTQSTEKDFRPL
LMTWWPSQETQRQYVNYMNAQLGINKTYDDTSNQLQLNIAAATIQAKIEA
KITTLKNTDWLRQTISAFVKTQSAWNSDSEKPFDDHLQNGAVLYDNEGKL
TPYANSNYRILNRTPTNQTGKKDPRYTADNTIGGYEFLLANDVDNSNPVV
QAEQLNWLHFLMNFGNIYANDPDANFDSIRVDAVDNVDADLLQIAGDYLK
AAKGIHKNDKAANDHLSILEAWSDNDTPYLHDDGDNMINMDNKLRLSLLF
SLAKPLNQRSGMNPLITNSLVNRTDDNAETAAVPSYSFIRAHDSEVQDLI
RDIIKAEINPNVVGYSFTMEEIKKAFEIYNKDLLATEKKYTHYNTALSYA
LLLTNKSSVPRVYYGDMFTDDGQYMAHKTINYEAIETLLKARIKYVSGGQ
AMRNQQVGNSEIITSVRYGKGALKATDTGDRTTRTSGVAVIEGNNPSLRL
KASDRVVVNMGAAHKNQAYRPLLLTTDNGIKAYHSDQEAAGLVRYTNDRG
ELIFTAADIKGYANPQVSGYLGVWVPVGAAADQDVRVAASTAPSTDGKSV
HQNAALDSRVMFEGFSNFQAFATKKEEYTNVVIAKNVDKFAEWGVTDFEM
APQYVSSTDGSFLDSVIQNGYAFTDRYDLGISKPNKYGTADDLVKAIKAL
HSKGIKVMADWVPDQMYAFPEKEVVTATRVDKFGKPVEGSQIKSVLYVAD
SKSSGKDQQAKYGGAFLEELQAKYPELFARKQISTGVPMDPSVKIKQWSA
KYFNGTNILGRGAGYVLKDQATNTYFNI
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8fk4 Chain G Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8fk4 The catalytic domains of Streptococcus mutans glucosyltransferases: a structural analysis
Resolution3.25 Å
Binding residue
(original residue number in PDB)		E405 D411 N455 V456 D933
Binding residue
(residue number reindexed from 1)		E186 D192 N236 V237 D714
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.5: dextransucrase.
Gene Ontology
Molecular Function
GO:0046527 glucosyltransferase activity
Biological Process
GO:0009250 glucan biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8fk4, PDBe:8fk4, PDBj:8fk4
PDBsum8fk4
PubMed37158310
UniProtP08987|GTFB_STRMU Glucosyltransferase-I (Gene Name=gtfB)

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