Structure of PDB 7zvw Chain G Binding Site BS02

Receptor Information
>7zvw Chain G (length=422) Species: 644223 (Komagataella phaffii GS115) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQVYGADEINAVVLDASSYRTKIGYGSLDCPILNLPSYYGHQTKDGSEKF
IFEENSMLIPRPDYEIKKIMKDGIIDDFEGAVKQYNYMFDVLKLKPSEQP
ILVIESTQNEYEKKTALLKQLLKENKFVATFLIKNPTCVSFAHGRPNCLV
VDLGHDLVTITPILDGISLRKQVLGTHYAGAFLSQQLRQLLNHKGVEVVP
VYKVKSKVPTYFPDEAKFEERKYDFDISESFENFHKLRILREMKETLLQA
LPDSETEKLKEQETEEDTRYFEFPNGLNVPFTKYERVRLANSLFNPSEPY
TGESGPNIVVEGDKPRGLTSLVNQALNHLDVDLKPQLANNIILTGATSLI
PGVAERLNQELTAMNPGLKVRIHSSANVIERTCSAWIGGSILSSLGTFHQ
LWVSENEYDEVGAKKLIMDRFR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7zvw Chain G Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7zvw The structure of the NuA4-Tip60 complex reveals the mechanism and importance of long-range chromatin modification.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		S21 S22
Binding residue
(residue number reindexed from 1)		S17 S18
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0005524 ATP binding
GO:0042393 histone binding
Biological Process
GO:0006281 DNA repair
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
GO:0051382 kinetochore assembly
Cellular Component
GO:0000785 chromatin
GO:0000812 Swr1 complex
GO:0005634 nucleus
GO:0016514 SWI/SNF complex
GO:0031011 Ino80 complex
GO:0035267 NuA4 histone acetyltransferase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zvw, PDBe:7zvw, PDBj:7zvw
PDBsum7zvw
PubMed37550452
UniProtC4QXM9

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