Structure of PDB 7yrg Chain G Binding Site BS02

Receptor Information
>7yrg Chain G (length=113) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILE
YLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGV
IPHIHKSLIGKKG
Ligand information
>7yrg Chain J (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcaatatccacctgcagattctaccaaaagtgtatttggaaactgctcc
atcaaaaggcatgttcagcggaattccgctgaacatgccttttgatggag
cagtttccaaatacacttttggtagaatctgcaggtggatattgat
Receptor-Ligand Complex Structure
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PDB7yrg Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1.
Resolution4.2 Å
Binding residue
(original residue number in PDB)
V17 R19 R34 R80
Binding residue
(residue number reindexed from 1)
V8 R10 R25 R71
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:7yrg, PDBe:7yrg, PDBj:7yrg
PDBsum7yrg
PubMed37536340
UniProtP0C0S5|H2AZ_HUMAN Histone H2A.Z (Gene Name=H2AZ1)

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