Structure of PDB 7syp Chain G Binding Site BS02

Receptor Information
>7syp Chain G (length=191) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TPDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRK
AQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLV
NAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAF
RNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR
Ligand information
>7syp Chain z (length=249) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccugugaggaacuacugucuucacgcagaaagcgucuagccauggcguua
guaugagugucgugcagccuccaggacccccccucccgggagagccauag
uggucugcggaaccggugaguacaccggaaugauuugggcgugcccccgc
aagacugcuagccgaguaguguugggucgcgaaaggccuugugguacugc
cugauagggugcuugcgagugccccgggaggucucguagaccgugcacc
<<<<.<<<<.....<<<<...<<<.<<....<<<<<.......>>>>>..
...>>.>>>....>>>>>>>>>>>>......<<<<<<<<<<<.<<<<<<<
<<<<<<<<<<..<<<<<<....>>>>>><<<.>>>.<<<<..>>>>>>>>
>.>>>>>>>><<<.....<<<......>>>....>>>....>>>>.>><<
<<....>>>><<..(((((.>>>>>>>>>>>.)))))............
Receptor-Ligand Complex Structure
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PDB7syp Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Resolution4.0 Å
Binding residue
(original residue number in PDB)
R130 G132 V134 R135 S184 N186 K191
Binding residue
(residue number reindexed from 1)
R117 G119 V121 R122 S171 N173 K178
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:7syp, PDBe:7syp, PDBj:7syp
PDBsum7syp
PubMed35822879
UniProtG1TFM5|RS5_RABIT Small ribosomal subunit protein uS7 (Gene Name=RPS5)

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