Structure of PDB 7s0s Chain G Binding Site BS02

Receptor Information

>7s0s Chain G (length=182) Species: 1772 (Mycolicibacterium smegmatis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KALPRLKQRYREEIREALQQEFNYANVMQIPGVVKVVVNMGVGDAARDAK
LINGAINDLALITGQKPEVRRARKSIAQFKLREGMPIGARVTLRGDRMWE
FLDRLISIALPRIRDFRGLSPKQFDGTGNYTFGLNEQSMFHEIDVDSIDR
PRGMDITVVTTATNDAEGRALLRALGFPFKEN

Ligand information

>7s0s Chain i (length=118) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

guuacggcgguccauagcggcagggaaacgcccggucccaucccgaaccc
ggaagcuaagccugccagcgccgaugauacuacccauccggguggaaaag
uaggacaccgccgaacac

<<<.<<<<<<<.....<<<<<<<<.....<<<<<...............>
>>..>>....>>>>>>.>>.<<.......<<<<<<....>>>>>>.....
..>>..>>>>>>>>>>..

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7s0s 50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA.
Resolution	3.05 Å
Binding residue (original residue number in PDB)	N31 M33 Q34 Q70 K71 E73 R95 T97 R99 R102
Binding residue (residue number reindexed from 1)	N26 M28 Q29 Q65 K66 E68 R90 T92 R94 R97

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:7s0s, PDBe:7s0s, PDBj:7s0s
PDBsum	7s0s
PubMed	35357969
UniProt	A0QSG1\|RL5_MYCS2 Large ribosomal subunit protein uL5 (Gene Name=rplE)

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