Structure of PDB 7a24 Chain G Binding Site BS02

Receptor Information
>7a24 Chain G (length=382) Species: 3712 (Brassica oleracea) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FTLNFGPQHPAAHGVLRLVLEMNGEVVERAEPHIGLLHRGTEKLIEYKTY
LQALPYFDRSDYVSMMAQEHAYSLAVEKLLNCEVPLRAQYIRVLFCEITR
ILNHLLALTTHAMDVGALTPFLWAFEEREKLLEFYERVSGARMHASFIRP
GGVAQDLPLGLCRDIDSFTQQFASRIDELEEMLTGNRIWKQRLVDIGTVT
AQQAKDWGFSGVMLRGPGVCWDLRRAAPYDVYDQLDFDVPVGTRGDCYDR
YCIRIEEMRQSLRIIVQCLNQMPSGMIKADDRKLCPPSRCRMKLSMESSI
HHFELYTEGFSVPASSTYTAVEAPKGEFGVFLVSNGSNRPYRCKIRAPGF
AHLQGLDFMSKHHMLADVVTIIGTQDIVFGEV
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7a24 Chain E Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7a24 Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		R69 H154
Binding residue
(residue number reindexed from 1)		R59 H144
Annotation score1
Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0016491 oxidoreductase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0048038 quinone binding
GO:0051287 NAD binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0045271 respiratory chain complex I

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7a24, PDBe:7a24, PDBj:7a24
PDBsum7a24
PubMed33060577
UniProtP93306|NDUS2_ARATH NADH dehydrogenase [ubiquinone] iron-sulfur protein 2 (Gene Name=NAD7)

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