Structure of PDB 6xfa Chain G Binding Site BS02

Receptor Information

>6xfa Chain G (length=406) Species: 10376 (human gammaherpesvirus 4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DFVPWTVDNLKSQFEAVGLLMAHSYLPANAEEGIAYPPLVHTYESLSPAS
TCRVCDLLDTLVNHSDAPVAFFEDYALLCYYCLNAPRAWISSLITGMDFL
HILIKYFPMAGGLDSLFMPSRILAIDIQLHFYICRCFLPVSSSDMIRNAN
LGYYKLEFLKSILTGQSPANFCFKSMWTKADYCGLLLGTWQGTDLLGGPG
AELALAITRPEAGDHSQGPCLLAPMFGLRHKNASRTICPLCESLGAHPDA
KDTLDRFKSLILDSFGNNIKILDRIVFLIKTQNTLLDVPCPRLRAWLQMC
TPQDFHKHLFCDPLCAINHSITNPSVLFGQIYPPSFQAFKAALAAGQNLE
QGVCDSLITLVYIFKSTQVARVGKTILVDVTKELDVVLRIHGLDLVQSYQ
TSQVYV

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

6xfa Chain G Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6xfa A pentameric protein ring with novel architecture is required for herpesviral packaging.
Resolution	3.6 Å
Binding residue (original residue number in PDB)	C316 C319 H386 C393
Binding residue (residue number reindexed from 1)	C238 C241 H308 C315
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0046872	metal ion binding

	Cellular Component
GO:0019031	viral envelope
GO:0030430	host cell cytoplasm
GO:0042025	host cell nucleus

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Molecular Function

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Cellular Component

External links

PDB	RCSB:6xfa, PDBe:6xfa, PDBj:6xfa
PDBsum	6xfa
PubMed	33554858
UniProt	P03184\|UL32_EBVB9 Packaging protein UL32 homolog (Gene Name=BFLF1)

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