Structure of PDB 6m4x Chain G Binding Site BS02

Receptor Information

>6m4x Chain G (length=207) Species: 6500 (Aplysia californica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVD
LVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQV
LSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSG
FEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLV
VKFRERR

Ligand information

>6m4x Chain H (length=16) Species: 89426 (Conus lividus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

GCCSHPACAVDHPEIC

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6m4x The crystal structure of Ac-AChBP in complex with LvIA analogs reveals the mechanism of its selectivity towards different nAChR subtypes
Resolution	2.998 Å
Binding residue (original residue number in PDB)	W145 S148 Y186 C188 C189 E191 Y193
Binding residue (residue number reindexed from 1)	W146 S149 Y187 C189 C190 E192 Y194

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004888	transmembrane signaling receptor activity
GO:0005216	monoatomic ion channel activity
GO:0005230	extracellular ligand-gated monoatomic ion channel activity

	Biological Process
GO:0006811	monoatomic ion transport
GO:0034220	monoatomic ion transmembrane transport

	Cellular Component
GO:0016020	membrane

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External links

PDB	RCSB:6m4x, PDBe:6m4x, PDBj:6m4x
PDBsum	6m4x
PubMed
UniProt	Q8WSF8

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