Structure of PDB 6c66 Chain G Binding Site BS02

Receptor Information
>6c66 Chain G (length=832) Species: 269800 (Thermobifida fusca YX) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPLDLRFWAKERGLRGKTYPLVCHSLDAAAAALVLWNEYLSPGLRDTIAS
SMETDEEHAGHCIAFWAGLHDIGKLTREFQQQIAIDLSAYPGEELSGEQR
SHAAATGKWLPFALPSLGYPNGGLVTGLVAQMLGGHHGTFHPHPSFQSRN
PLAEFGFSSPHWEKQRHALLHAVFDATGRPTPPDMLDGPTASVVCGLVIL
ADWLVSQEDFLLERLTSLPADGSASALRAHFETSLRRIPSLLDAAGLKPN
GLQASLAKHLPCLCTGPGLVLITAPMGEGKTEAAYHVADLLGKATGRPGR
FLALPTMATADQMHTRLKEYAMGRKRGLLAPWAVGTIDQALMAVLRAKHN
ALRLFGLAGKVVVVDEAHAVDPYMQVLLEQLLRWLGTLDVPVVLLSATLH
HSIANSLVKAYLEGARGRRWNRSEPQPVSEVSYPGWLHVDARIGKVTRSS
DVDPLPIATTPRKPLEVRLVDVPVKEGALNRSTVLAKELTPLVKQAAIIC
TTVAEAQGVYDLLSQWFATLPDLYLLHSRFPNRQRTEITATIVDLFGKEG
AQSGRRPTVLVATQVVEQSLDLDVDLMISDLAPVSLLLQRAGRCWRHEHL
GIINRPQWAKQPELVVLTPEQNRAPWFPRSWTSVYPLALLQRTYTLLRRR
NGAPVQIPEDVQQLVDDVYDDDSLAEDLEADMERMGEELAQRGLARNAVI
PDPDDAEDNLNGLTEFATRFGAGSVRVLCYYVGNRWLDPECTVEFPEQGT
GREGRFTMADCRDLVARTIPVRMGPWASQLTEDNHPPEAWRESFYLRDLV
LIPQRVTDEGAVLPTETGGREWLLDPCKGLIF
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain6c66 Chain G Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6c66 Structure basis for RNA-guided DNA degradation by Cascade and Cas3.
Resolution3.66 Å
Binding residue
(original residue number in PDB)		H83 D84 H115 H149 D215
Binding residue
(residue number reindexed from 1)		H70 D71 H102 H136 D202
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0051607 defense response to virus
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6c66, PDBe:6c66, PDBj:6c66
PDBsum6c66
PubMed29880725
UniProtQ47PJ0

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